![]() Values above 200 pg/mL were considered normal. Hypocretin-1 levels below 110 pg/mL were diagnostic for narcolepsy. Results HLA-DQB1*0602 frequency was increased in narcolepsy with typical cataplexy (93% vs 17% in controls), narcolepsy without cataplexy (56%), and in essential hypersomnia (52%). Main Outcome Measures Diagnostic threshold for CSF hypocretin-1, HLA-DQB1*0602 positivity, and clinical and polysomnographic features. Intervention Venopuncture for HLA typing, lumbar puncture for CSF analysis, primary diagnosis using the International Classification of Sleep Disorders, Stanford Sleep Inventory for evaluation of narcolepsy, and sleep recording studies. The subject group also included 296 controls (healthy and with neurological disorders). ![]() Participants There were 274 patients with narcolepsy hypersomnia obstructive sleep apnea restless legs syndrome insomnia and atypical hypersomnia cases such as familial cases, narcolepsy without cataplexy or without HLA-DQB1*0602, recurrent hypersomnias, and symptomatic cases (eg, Parkinson disease, depression, Prader-Willi syndrome, Niemann-Pick disease type C). Setting Sleep disorder and neurology clinics in the United States and Europe, with biological testing performed at Stanford University, Stanford, Calif. Clinical and demographic features were compared in narcoleptic subjects with and without low CSF hypocretin-1 levels. Signal detection analysis was used to determine the CSF hypocretin-1 levels best predictive for International Classification of Sleep Disorders (ICSD)–defined narcolepsy (blinded criterion standard). Objectives To delineate the spectrum of the hypocretin deficiency syndrome and to establish CSF hypocretin-1 measurements as a diagnostic tool for narcolepsy.ĭesign Diagnosis, HLA-DQ, clinical data, the multiple sleep latency test (MSLT), and CSF hypocretin-1 were studied in a case series of patients with sleep disorders from 1999 to 2002. Shared Decision Making and CommunicationĬontext Narcolepsy, a neurological disorder affecting 1 in 2000 individuals, is associated with HLA-DQB1*0602 and low cerebrospinal fluid (CSF) hypocretin (orexin) levels.Scientific Discovery and the Future of Medicine.Health Care Economics, Insurance, Payment.Clinical Implications of Basic Neuroscience.Challenges in Clinical Electrocardiography.
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![]() ![]() In surveys, these would-be resolvers repeatedly say that if only they had more self-determination, they would've overcome any hurdles and achieved their goals.īut writing at the Los Angeles Times, Berdik points to an emerging body of research that willpower is malleable. More often than not, people who fail to keep their resolutions blame their own lack of willpower. To be clear: Simply setting a goal does raise your chances of achieving that goal, significantly.īut within weeks or months, people begin abandoning their resolutions as they hit bumps in the road that throw them off their stride. And "in our increasingly lives, social media can be used as a motivator," she argues. Sharing the resolutions "was a good way to hold myself to them," Rivka told me. My friend Rivka Friedman, who authors a cooking blog called Not Derby Pie, used a similar tactic several years ago: She posted her " kitchen resolutions." You can still see them on the right-hand side of the blog, as Rivka either crossed off her accomplishments or hyperlinked to blog posts, like her efforts to learn how to " make kimchi" or " fillet a fish (properly)." As part of that effort, Newell Jones launched a blog, And Then We Saved, to chronicle her attempt to go from shopaholic to spendthrift in less than a year and a half, she'd paid off her debt. It's another way to build accountability, especially in the Facebook era.įor example, after a woman named Anna Newell Jones ran more than $23,600 into debt, she made a New Year's resolution to work her way out of it-and publicly. For some, making a clear to-do list is enough of a reminder others rely on " vision boards" or personal diaries.Īn emerging tactic: share your goals with your friends and family. "We say if you can't measure it, it's not a very good resolution because vague goals beget vague resolutions," says John Norcross of the University of Scranton.Įxperts recommend charting your goals in some fashion, although there's no universal strategy for success. Don't say you're "going to start going to the gym" in 2013-set a clear ambition, like attending a weekly spin class or lifting weights every Tuesday or Thursday. "It is much easier to follow a plan that says no potato chips, fries, or ice cream for six weeks."Īnd be specific. "A resolution to lose some weight is not that easy to follow," notes Roy Baumeister, a social psychologist. That's why goals should be bounded by rational, achievable metrics. Setting ambitious resolutions can be fun and inspiring, but the difficulty in achieving them means that your elation can quickly give way to frustration. "Remember, it is not the extent of the change that matters, but rather the act of recognizing that lifestyle change is important and working toward it, one step at a time," Bufka adds. "I think my earlier laundry lists made it easier to abandon."Īnd it's more sensible to set "small, attainable goals throughout the year, rather than a singular, overwhelming goal," according to psychologist Lynn Bufka. So "this year, I'm keeping my resolution list short," says Chris Berdik, a science journalist and the author of " Mind Over Mind. Essentially, shooting for the moon can be so psychologically daunting, you end up failing to launch in the first place. What are your interests, do you have any personal skills worth mentioning? This is your opportunity to persuade the company you are right for this position.That's a nice aspiration, experts say-but the average person has so many competing priorities that this type of approach is doomed to failure. ![]() Recruiters will be inundated with CVs in January so don’t be afraid to add a personal touch to your application. Whilst companies want to know if you can do the job, they also want to know how you will fit into their office culture. They want to be able to see on paper that you are a perfect match for their company, so make sure you target the right roles for your skillset. Know the company inside and out before you apply, understand their vision, values and ethos and align your application to theirs. Ensuring you highlight your strengths and achievements that are most in line with the job you are applying for. Tailor your CV for each company you apply for. What are your strengths, passions and goals? Highlight your achievements not just your responsibilities. Spend some time thinking about what makes you different from your peers. If you are amongst the January crowd and looking for a new role, how do you stand out? Now is the time to really launch your inner salesperson, market yourself and get noticed! ‘Find a new job’ is one of the most common new year’s resolutions and is always the busiest time of year for us recruiters. where it has nothing to do with us, or if it’s messaging on it, we try to stay out of that too.” “It’s one thing to inspire people about space exploration. “It’s just a question of how we’re perceived and how it represents us,” he said. ![]() The agency usually doesn’t permit underwear with NASA logos, and Ulrich said the agency recently denied a T-shirt with the NASA meatball and an illustration of astronauts in space, cheering with red cups. The meatball logo can never be pictured with the NASA worm because they are from two different time periods and would never have appeared together contemporaneously.Īnd NASA mission imagery must be used with the appropriate agency logo of the time - Apollo-era elements must be used only with the meatball logo, not the worm.Īny request involving tobacco or alcohol is denied, Ulrich said.īeyond that, there are some subjective assessments of potential projects. Logo and background colors are strictly regulated and derivations of the traditional insignia - such as an item spelling out “NERD” rather than “NASA” on the meatball logo - are not permitted. NASA logos cannot appear together with insignia from other brands, to avoid the perception that NASA is endorsing a specific company or product. Ulrich and his co-worker approve merchandise requests based on a few, different criteria. This spring, he requested additional help to deal with the approval requests and now has a co-worker involved, which has been especially helpful because the 50th anniversary of the Apollo 11 moon landing has made things “quite busy,” Ulrich said. The approval process can be as short as a few hours or as long as a couple of days, Ulrich said. To use either NASA logo on merchandise, companies submit designs to the agency for approval. The National Park Service, for example, does not allow its arrowhead symbol - the brown insignia depicting a green tree, a snowy mountain and a buffalo - to be licensed for consumer merchandise. Use of federal agency logos on consumer products is not the same across the board. It deals with space exploration - things that I feel the entire world could benefit from, not just our country.” ![]() “It almost doesn’t feel like it’s part of the government, even though I know it is,” said Reza, a middle-school teacher who lives in Chino. But he said he wouldn’t wear promotional clothing with logos from other federal agencies, at least under the current government. This month, he bought a similar shirt from Urban Outfitters. ![]() Last year, space enthusiast Edwin Reza, 31, bought a black T-shirt featuring the NASA meatball logo from a discount retail store. “A lot of people, I think, were quite nostalgic for this logo.” “If you grew up in the ’80s or early ’90s or the ’70s, this logo is what NASA looks like in your mind,” Smyth said. Generally speaking, the baggier the T-shirt, the more casual your outfit will look.įor a smarter aesthetic, turn your attention to something fitted.The worm logo has a cult following in the branding and design industry, said Hamish Smyth, who co-founded the publishing house Standards Manual, which produced a coffee-table book about it.Īnd it taps into the childhood wonder that generations of Americans have had about space. This depends on personal preference, so you need to decide what type of look you want to go for. Not only will you notice the difference when you wear it, but you’ll also get more bang for your buck.Ĭotton should be your first choice, while the cotton jersey is a popular option it feels great while offering optimum durability and enough stretch to keep you comfortable. This goes for any purchase you make, but be sure to invest in quality. It’s all about balance, so if you’re choosing a modest print, keep the rest of your look simple to allow it to take some of the attention. Your graphic doesn’t have to be big, it simply needs to be significant in comparison to the rest of your outfit. Honestly guys, size really doesn’t matter. ![]() What makes the best graphic tees? Here are three key things to consider before dishing out the dollars. 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You can rub this marinade onto the chops on both sides before proceeding to sear or pan fry the chops for a quick weeknight dish.Īnother consideration is to avoid overcrowding the pan or skillet with the pork chops while cooking. Instead of frying the chops plain, for example, you can marinate them for a short while using very simple marinades.Īn example of a simple, easy-to-make marinade would be a crushed mixture of sage, rosemary, garlic, and black pepper combined with a wet ingredient such as olive oil. Using a meat thermometer, the pork chop’s internal temperature should be 145° or 62.8☌.įurthermore, recipes with pork chops generally taste better when marinated. The key to unlocking perfectly cooked pork chops is watching the internal temperature of the chops. On the other hand, thin pork chops easily become dry and tough when cooked, especially using the wrong method. Thicker chops hold more flavor and remain juicy inside when cooked. One of the best ways of cooking pork chops of a suitable cut such as Rib chops is to make sure there are double chops in thickness of no less than an inch. Unless you cook the right cut the right way, you would end up with dry, uninteresting, and frankly boring pork chops. This cut is typically suitable for weeknight dinners because it cooks fast and is thus ideal for putting a meal together quickly. The best way to cook Rib pork chops is by quick searing, broiling, or pan-frying.
You have fewer combinations than permutations.Let us say there are five flavors of icecream: banana, chocolate, lemon, strawberry and vanilla. Combinations sound simpler than permutations, and they are. P(10,3) = 720.ĭon’t memorize the formulas, understand why they work. Permutation: Listing your 3 favorite desserts, in order, from a menu of 10. Permutation: Picking a President, VP and Waterboy from a group of 10. Here’s a few examples of combinations (order doesn’t matter) from permutations (order matters).Ĭombination: Picking a team of 3 people from a group of 10. Writing this out, we get our combination formula, or the number of ways to combine k items from a set of n: Which means “Find all the ways to pick k people from n, and divide by the k! variants”. In our case, we get 336 permutations (from above), and we divide by the 6 redundancies for each permutation and get 336/6 = 56. If we want to figure out how many combinations we have, we just create all the permutations and divide by all the redundancies. So, if we have 3 tin cans to give away, there are 3! or 6 variations for every choice we pick. If you have N people and you want to know how many arrangements there are for all of them, it’s just N factorial or N! Wait a minute… this is looking a bit like a permutation! You tricked me! So we have $3 * 2 * 1$ ways to re-arrange 3 people. ![]() Well, we have 3 choices for the first person, 2 for the second, and only 1 for the last. For a moment, let’s just figure out how many ways we can rearrange 3 people. This raises an interesting point - we’ve got some redundancies here. Either way, they’re equally disappointed. If I give a can to Alice, Bob and then Charlie, it’s the same as giving to Charlie, Alice and then Bob. Well, in this case, the order we pick people doesn’t matter. ![]() How many ways can I give 3 tin cans to 8 people? In fact, I can only afford empty tin cans. ![]() Let’s say I’m a cheapskate and can’t afford separate Gold, Silver and Bronze medals. If we have n items total and want to pick k in a certain order, we get:Īnd this is the fancy permutation formula: You have n items and want to find the number of ways k items can be ordered:Ĭombinations are easy going. Where 8!/(8-3)! is just a fancy way of saying “Use the first 3 numbers of 8!”. What’s another name for this? 5 factorial!Īnd why did we use the number 5? Because it was left over after we picked 3 medals from 8. This is where permutations get cool: notice how we want to get rid of $5 * 4 * 3 * 2 * 1$. Unfortunately, that does too much! We only want $8 * 7 * 6$. To do this, we started with all options (8) then took them away one at a time (7, then 6) until we ran out of medals. The total number of options was $8 * 7 * 6 = 336$. We picked certain people to win, but the details don’t matter: we had 8 choices at first, then 7, then 6. Silver medal: 7 choices: B C D E F G H. ![]() Gold medal: 8 choices: A B C D E F G H (Clever how I made the names match up with letters, eh?).We’re going to use permutations since the order we hand out these medals matters. How many ways can we award a 1st, 2nd and 3rd place prize among eight contestants? (Gold / Silver / Bronze) We’re using the fancy-pants term “permutation”, so we’re going to care about every last detail, including the order of each item. Let’s start with permutations, or all possible ways of doing something. ![]() Once you are done, you can play around with an array of 3D, screen resolution, and tiling options available, and choose one that befits you. Thankfully, with the help of the iDownloadBlog Wallpapers of the Week community, we have the official iPhone 13 and iPhone 13 Pro wallpapers for iOS 15, extracted from the final release candidate. Right-click the image and select the option to set it as your background. 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While each show and movie selected was chosen based on its appropriateness for a younger teen audience, we acknowledge the definition of appropriate changes from household to household. Some will deal with lighter topics while others cover issues that many teens deal with like peer pressure, inequality, discrimination, identity, grief, and relationship exploration (romantic and sexual). The list is comprised of sitcoms, dramas, romances, and coming-of-age stories. So, we’ve compiled a list of Netflix teen shows and movies suitable for younger teens. The same can be said for parents not comfortable with their 13 year old watching Riverdale but highly aware that Nickelodeon, Disney, and Cartoon Network are about to become staples of the past for their maturing child. However, it does makes it difficult for teens searching for content skewed more toward their age group. Where does that leave 13-15-year-old Netflix users? Most likely not up a creek without a paddle as some of them are tuning into these shows anyway with or without their parents’ permission. While that categorization can be based on the amount of adult language, drug/alcohol use, and blood/gore in a title like Fate: The Winx Saga, it can also be determined by sexual content and nudity in a title like Tiny Pretty Things. Netflix teen shows and movies draw large audiences and often huge followings.īut, it must also be acknowledged that the streamer’s most popular teen content is more often than not rated MA. Arguably, their the best place to find a diverse range of teen media period. No other streaming network is consistently churning out content for the 13-18 year old age demographic like they are.įrom YA adaptations to teen rom-coms, Netflix has the market cornered on where to go for the best content for teenagers not found on network television. It should be universally acknowledged that Netflix is the best streaming platform for teen movies and shows. Work It - Courtesy of Brendan Adam-Zwelling/Netflix Netflix teen movies and shows for 13-15-year-olds ![]() Do the same for contrasting the two pieces – start small. Then the comparison can include attention to detail so use of color, subject matter, or iconography. It is always best to start with smaller comparisons between the two works of art such as the medium of the piece. Most introductory art history classes will ask students to write a compare and contrast essay about two pieces – examples include comparing and contrasting a medieval to a renaissance painting. Two statues in the same region, have throughout history, changed in their style. Venus was normally defined as “golden,” so her hair would have been painted. It is also possible she had a tiara and bracelets. Venus was noted for loving necklaces, so it is very possibly she would have had one. She had earrings that were brutally stolen, ripping her ears away. The Venus de Milo had a band around her right bicep. She seems be firmly planted into the earth, and since she is looking at the left, her big features such as her waist define her. From her right side she seems almost like a pillar and her leg bears most of the weight. ![]() Viewing the Venus de Milo, she changes from side to side. Though her body shows to be heavy, she still seems to almost be weightless. Her hips suggest that she has had several children. The Venus from head to toe is six feet seven inches tall. A largely contrasting Greek statue to the korai is the Venus de Milo. From about 530, most wear a thinner, more elaborate, and brightly painted Ionic linen and himation. The earliest korai wore the simpler Dorian peplos, which was a heavy woolen garment. The statue wears a tight-fitted, belted peplos, giving the body a very plain look. The earliest korai is a Naxian women to Artemis. In the mid-seventh century to the early fifth, life-sized standing marble statues of young women, often elaborately dress in gaily painted garments were created known as korai. The following is a brief stylistic analysis of two Greek statues, an example of how style has changed because of the “essence of the age.” Over the years, sculptures of women started off as being plain and fully clothed with no distinct features, to the beautiful Venus/Aphrodite figures most people recognize today. Style can distinguish an artist’s work from others and within their own timeline, geographical regions, etc. It is also ideal to discuss the focal of the piece – what is in the center? What stands out the most in the piece or takes up most of the composition?Ī stylistic approach can be described as an indicator of unique characteristics that analyzes and uses the formal elements (2-D: Line, color, value, shape and 3-D all of those and mass).The point of style is to see all the commonalities in a person’s works, such as the use of paint and brush strokes in Van Gogh’s work. Again, it is best to be organized and focused in your writing – if you discuss the animals and then the individuals and go back to the animals you run the risk of making your writing unorganized and hard to read. First summarize the overall appearance of the work of art – is this a painting? Does the artist use only dark colors? Why heavy brushstrokes? etc and then discuss details of the object – this specific animal is gray, the sky is missing a moon, etc. ![]() Organize your information and focus on each feature before moving onto the text – it is not ideal to discuss color and jump from line to then in the conclusion discuss color again. How does an artist convey this same information? Questions to consider in a formal analysis is how do all these elements come together to create this work of art? Think of formal analysis in relation to literature – authors give descriptions of characters or places through the written word. This includes the individual design elements – composition, color, line, texture, scale, contrast, etc. ![]() Typically in an art history class the main essay students will need to write for a final paper or for an exam is a formal or stylistic analysis.Ī formal analysis is just what it sounds like – you need to analyze the form of the artwork. Art History Analysis – Formal Analysis and Stylistic Analysis These OWL resources provide guidance on typical genres with the art history discipline that may appear in professional settings or academic assignments, including museum catalog entries, museum title cards, art history analysis, notetaking, and art history exams. Writing Letters of Recommendation for Students. |
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